Progynova

Progynova

estradiol

Manufacturer:

Bayer HealthCare Pharma

Distributor:

DKSH
Concise Prescribing Info
Contents
Estradiol valerate
Indications/Uses
HRT for natural menopause or after ovariectomy. Prevention of postmenopausal osteoporosis.
Dosage/Direction for Use
1 tab is taken daily starting on the 1st day of menstruation. In women w/ intact uterus, the concomitant use of an appropriate progestogen is advised for 10-14 days every 4 wk.
Administration
Should be taken with food.
Contraindications
Pregnancy & lactation, liver disease, undiagnosed vag bleeding, previous or existing liver tumours; thromboembolic disorder, existing or suspected hormone-dependent tumours of the uterus or breast; hypertriglyceridemia.
Special Precautions
Suspected adenoma of the anterior lobe of the pituitary gland. History of thrombosis; overwt; varicose veins; fibroids of the womb; endometriosis; liver/gallbladder disease; jaundice; diabetes; HTN, chloasma, epilepsy, benign breast cancer; asthma; migraine, porphyria, otosclerosis, SLE; chorea minor.
Adverse Reactions
Breast tenderness or enlargement, breakthrough bleeding, spotting; dysmenorrhea, changes in vag secretion; GI disorders; skin & SC tissue disorders; headaches, migraine, dizziness, depression, fatigue; changes in body wt & libido.
Drug Interactions
Antiepileptic drugs (barbiturates, hydantoins, carbamazepine), antidiabetic agents, rifampicin, antibiotics (penicillins & tetracyclines).
MIMS Class
Oestrogens, Progesterones & Related Synthetic Drugs
ATC Classification
G03CA03 - estradiol ; Belongs to the class of natural and semisynthetic estrogens used in estrogenic hormone preparations.
Presentation/Packing
Form
Progynova tab 1 mg
Packing/Price
3 × 28's
Form
Progynova tab 2 mg
Packing/Price
3 × 28's
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