Praze Dosage/Direction for Use

Recommended Dose: Adult: Usually, for adults, one vial of PRAZE (30 MG INJECTION) is mixed with isotonic sodium chloride solution (NSS) or 5% dextrose in water (D5W) and administered by intravenous injection or intravenous drip twice a day.
Pediatric: The safety of Lansoprazole IV in children has not been established.
Geriatric: Since physiological function is generally decreased in elderly patients. Lansoprazole IV should be carefully administered in elderly patients.
Patients with renal impairment: Dosage adjustment is not necessary.
Patients with hepatic impairment: Dosage reduction should be considered in patients with severe hepatic impairment (Child-Pugh class C).
Mode of Administration: Directions for use: 1. Intravenous injection: Use 5 - 10 ml NSS or D5W to mix with PRAZE (30 MG INJECTION) shake the vial gently until getting clear and colorless solution. Then draw all solution back and gently inject intravenously over 2 minutes.
2. Intravenous drip: Use 5 - 10 ml NSS or D5W to mix with PRAZE (30 MG INJECTION) shake the vial gently until getting clear and colorless solution.
Then draw all solution back and mix with NSS or D5W 100 ml and then administer by intravenous drip.
Stability after reconstitution: PRAZE (30 MG INJECTION) should be used immediately after reconstitution in compatible infusion solutions and the dissolved solution should not be stored.
For intravenous drip: Mixing with NSS, drip the solution within 12 hours; mixing with D5W, drip the solution within 5 hours.