Adjunct to diet alone or in combination w/ other lipid lowering therapy in adults w/ heterozygous familial & non-familial hypercholesterolaemia or patients who are unable to reach LDL-C goals w/ max tolerated dose; statin-intolerant.
SC 75 mg once every 2 wk. Patients requiring larger LDL-C reduction (>60%) 150 mg once every 2 wk, or 300 mg once every 4 wk. Additional LDL-C reduction Adjust dose to a max of 150 mg once every 2 wk.
Not to be inj into active skin disease areas or injury eg, sunburns, skin rashes, inflammation or infections. Not to be co-administered w/ other inj products at the same inj site. Discontinue treatment if serious allergic reactions occur. Severe renal (estimated GFR <30 mL/min/1.73 m2) & hepatic (Child-Pugh C) impairment. Not recommended during pregnancy & lactation. Childn & adolescents <18 yr.
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