Adult & elderly Active duodenal, active benign gastric & anastomotic ulcers 10-20 mg once daily in the morning.
Erosive or ulcerative GERD 10-20 mg once daily for 4-8 wk.
Reflux esophagitis patients 10-20 mg bid for a further 8 wk, when PPI treatment is ineffective.
Patients w/ severe mucosa injury 20 mg bid.
GERD maintenance Maintenance: 10-20 mg once daily depending upon patient response.
Symptomatic treatment of moderate to very severe GERD 10 mg once daily. When symptom has resolved, use as on-demand regimen for subsequent symptom control.
Zollinger-Ellison syndrome Individualized dosage. Initially 60 mg daily. Doses up to 100 mg daily or 60 mg bid have been used.
Eradication of H. pylori Pariet 20 mg bid + clarithromycin 500 mg bid + amoxicillin 1 g bid for 7 days.
Adult Prevention of gastric & duodenal ulcer associated w/ low-dose aspirin therapy 10 mg once daily.
Adolescent ≥12 yr Short-term (up to 8 wk) treatment of GERD 20 mg once daily up to 8 wk.