SC Adult Symptoms associated w/ carcinoid tumors w/ features of carcinoid syndrome, VIPomas, glucagonomas, gastro-entero-pancreatic endocrine tumors Initially 50 mcg (0.05 mg) once daily to bid adjusted based on response. May be increased to 200 mcg tid.
Discontinue after 1 wk if no effect in carcinoid tumors.
Acromegaly, short term treatment before pituitary surgery or long-term treatment in those inadequately controlled by other treatment or by RT or until RT become fully effective 100-200 mcg tid. Discontinue if no response w/in 3 mth.
Prevention of complication following pancreatic surgery 100 mcg tid for 7 consecutive days starting on the day of operation at least 1 hr prior to laparotomy.
HIV-associated diarrhea Initially 100 mcg tid, may be titrated to 250 mcg tid if diarrhoea is not controlled after 1 wk.
IV infusion Bleeding gastro-esophageal varices 25 mcg/hr for 5 days by continuous IV infusion.
Cirrhotic patients w/ bleeding gastro-esophageal varices Up to 50 mcg/hr for 5 days.
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