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Known hypersensitivity to nitroglycerin or other organic nitrates.
Hypotension or uncorrected hypovolemia as the use of nitroglycerin injection in such conditions could produce severe hypotension or shock.
Increased intracranial pressure (e.g. head trauma or cerebral hemorrhage).
Inadequate cerebral circulation, constrictive pericarditis and pericardial tamponade.
Concomitant administration of sildenafil.
Severe anaemia and arterial hypoxaemia.
