IV Inj: Bolus inj over approx 5 min. Infusion:Approx 15-30 min. AdultPneumonia, UTI, gynaecological, skin & skin structure infections 500 mg every 8 hr. Nosocomial pneumonias, peritonitis, infections in febrile neutropenic patients, septicaemia 1 g every 8 hr. Meningitis 2 g every 8 hr. Childn >3 mth to 12 yr 10-20 mg/kg every 8 hr. Childn weighing >50 kg Adult dose. Meningitis 40 mg/kg every 8 hr. Febrile episodes Neutropenic patients 20 mg/kg every 8 hr. Renal insufficiency w/ CrCl 26-50 mL/min Recommended dose every 12 hr, 10-25 mL/min ½ of recommended dose every 12 hr, <10 mL/min ½ of the recommended dose every 24 hr.
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