Rarely, hepatic effects (reversible increase in liver enzymes); hematologic effects (agranulocytosis, granulocytopenia, eosinophilia); GIT effects (stomatitis, nausea/vomiting, abdominal pain, diarrhea, anorexia); resp effects (cough, asthma attack); CNS effects (headache, perioral numbness, convulsions); others (oral dryness, vertigo, phlebitis).