Discontinue use if allergic or anaphylactic reactions is suspected. Do not administer w/o very close monitoring of hemodynamics (evidence of cardiac or resp failure, renal failure or increasing ICP). Decompensated cardiac insufficiency, HTN, esophageal varices, pulmonary edema, hemorrhagic diathesis, severe anemia, renal & post-renal failure. Immediately discontinue at 1st sign of CV overload (headache, dyspnea, jugular vein congestion) or increased BP, raised central venous pressure & pulmonary edema. Ensure adequate substitution of other blood constituents (coagulation factors, electrolytes, platelets & erythrocytes). Patients on controlled Na diet. Monitor patient's electrolyte status. Observe carefully injured or post-op patients in BP elevation after treatment administration. Ped patients. Pregnancy & lactation.