Stop treatment if hypersensitivity reactions or signs of intolerance occur; in patients w/ on-going bacteraemia; in case of paravenous leakage. Not to be administered by SC or IM route. Hypersensitivity reactions including serious & potentially fatal anaphylactic/anaphylactoid reactions; after previously uneventful doses of parenteral Fe complexes; risk of progression to Kounis syndrome. Symptomatic hypophosphataemia leading to osteomalacia & fractures requiring clinical intervention including surgery; worsening fatigue w/ myalgias or bone pain. Acute or chronic infection, asthma, eczema or atopic allergies. Patients w/ known allergies including drug allergies; history of severe asthma, eczema or other atopic allergy; immune or inflammatory conditions (eg, SLE, RA). Patients on Na-controlled diet. Monitor serum phosphate in patients receiving multiple administrations at higher doses or long-term treatment & w/ risk factors for hypophosphataemia; Fe status to avoid Fe overload. Avoid in patients w/ hepatic dysfunction where Fe overload is precipitating factor, ie, porphyria cutanea tarda. Pregnancy & lactation. Not recommended in childn <14 yr.