Faverin Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing Local Product Insert

Concise Prescribing Info

Contents

Fluvoxamine maleate

Indications/Uses

Major depressive episode, obsessive compulsive disorder (OCD).

Click to view Faverin detailed prescribing information

Dosage/Direction for Use

Depression Recommended starting dose: 50 or 100 mg as single dose in the evening. May gradually increase dose until an effective dose is reached. Effective dose: 100 mg/day adjusted on individual patient response. Max: 300 mg/day. Prevention of recurrence of depression 100 mg daily. Obsessive compulsive disorder Adult Recommended starting dose: 50 mg/day for 3-4 days. May be increased gradually until effective dosage is achieved. Max: 300 mg/day. If total daily dose is >150 mg, administer in 2 or 3 divided doses. Adolescents & childn 8 yr Starting dose: 25 mg/day preferably at bedtime. May be increased every 4-7 days in 25 mg increments until effective dose is achieved. Max: 200 mg/day. If total daily dose is >50 mg, administer in 2 divided doses.

Click to view Faverin detailed prescribing information

Overdosage

View Faverin overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Swallow whole w/ water, do not chew. Avoid high consumption of caffeine-containing beverages.

Contraindications

Hypersensitivity. Concomitant use w/ ramelteon, tizanidine & MAOIs.

Click to view Faverin detailed prescribing information

Special Precautions

Renal & hepatic impairment. Patients w/ other psychiatric disorders & history of suicide-related events. Akathisia/psychomotor restlessness may develop. History of convulsive disorders, DM, bleeding disorder & mania/hypomania. Avoid in patients w/ unstable epilepsy; monitor carefully patients w/ controlled epilepsy; discontinue use if seizures occur. Patients w/ raised IOP or at risk of narrow-angle glaucoma, taking SSRIs particularly in elderly. Concomitant use w/ drugs known to affect platelet function (eg, atypical antipsychotics & phenothiazines, TCAs, acetylsalicylic acid, NSAIDs) or drugs that increase risk of bleeding; terfenadine, astemizole or cisapride; electroconvulsive therapy. Avoid abrupt w/drawal. May impair ability to drive or use machinery. Pregnancy & lactation. Childn <18 yr except for patients w/ OCD, elderly.

Click to view Faverin detailed prescribing information

Use In Pregnancy & Lactation

Click to view Faverin detailed prescribing information

Adverse Reactions

Anorexia; agitation, nervousness, anxiety, insomnia, somnolence, tremor, headache, dizziness; palpitations, tachycardia; abdominal pain, constipation, diarrhoea, dry mouth, dyspepsia, nausea, vomiting; hyperhydrosis; asthenia, malaise.

Click to view Faverin detailed prescribing information

Drug Interactions

Risk of serotonin syndrome w/ MAOIs including linezolid. May inhibit metabolism of CYP450 drugs. Increase AUC of ramelteon. Concomitant use w/ drugs w/ narrow therapeutic index (eg, tacrine, theophylline, methadone, mexiletine, phenytoin, carbamazepine & cyclosporine). Increased plasma levels of TCAs (eg, clomipramine, imipramine, amitriptyline) & neuroleptics (eg, clozapine, olanzapine, quetiapine), benzodiazepines (eg, triazolam, midazolam, alprazolam & diazepam), caffeine. Increase plasma conc of ropinirole, propranolol & warfarin. Increased risk of QT-prolongation/Torsade de Pointes w/ terfenadine, astemizole or cisapride. Enhanced serotonergic effects w/ other serotonergic agents (eg, triptans, tramadol, SSRIs & St. John's wort prep) & lithium. Increased risk of haemorrhage w/ oral anticoagulants. Alcohol.

Click to view Faverin detailed prescribing information

Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Faverin detailed prescribing information

Storage

View Faverin storage conditions for details to ensure optimal shelf-life.

Description

View Faverin description for details of the chemical structure and excipients (inactive components).

Action

View Faverin mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antidepressants

ATC Classification

N06AB08 - fluvoxamine ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.

Thai FDA Category

Presentation/Packing

Form

Faverin FC tab 100 mg

Packing/Price

30's

Form

Faverin FC tab 50 mg

Packing/Price

60's

Faverin

fluvoxamine

Manufacturer:

Abbott

Distributor:

Zuellig Pharma