Adult Symptomatic anaemia associated w/ chronic renal failure Correction phase:
IV Initially 40 IU/kg thrice wkly. May be increased to 80 IU/kg thrice wkly after 4 wk, then increase to 25% of previous dose mthly.
SC Initially 20 IU/kg thrice wkly. May be increased to 40 IU/kg thrice wkly after 4 wk, then further increase to 25% of previous dose mthly until target Hb level is obtained. Maintenance phase:
IV Switch to twice wkly.
SC 1 inj wkly or thrice wkly.
IV/SC Max: Not to exceed 700 IU/kg wkly.
Symptomatic anaemia in cancer patients w/ non-myeloid malignancies receiving chemotherapy SC/IV Initially 20,000 IU once wkly. May be increased to 40,000 IU once wkly after 4 wk, then increase to 60,000 IU once wkly after an additional 4 wk. Max: Not to exceed 60,000 IU wkly. Treatment duration: Up to 4 wk after the end of chemotherapy.