SC Loading dose: 120 mg inj every 2 wk (1st dose at wk 0, 2nd dose at wk 2 & 3rd dose at wk 4). Maintenance dose: 120 mg inj every 4 wk.
Delayed or missed doses Last dose administered ≥12 wk: 120 mg inj at wk 0, 2 & 4, followed by 120 mg every 4 wk; 8 to <12 wk: 120 mg inj at wk 0 & 2, followed by 120 mg every 4 wk; <8 wk during the maintenance period or missed a loading dose: 120 mg inj as soon as possible. Maintenance period: Reset to every 4 wk. Loading period: If 2nd loading dose is delayed or missed: Administer as soon as possible & 3rd final dose after 2 wk; if 3rd loading dose is delayed or missed: Administer as soon as possible & 1st maintenance dose after 4 wk.
Restart of treatment after liver transaminase elevation Last dose administered ≥12 wk: Restart at 120 mg inj at wk 0, 2 & 4, followed by 120 mg every 4 wk; <12 wk: Restart at 120 mg inj every 4 wk.
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