IM Inj in deltoid region in adults & childn, or in anterolateral thigh in neonates, infants & young childn. Primary immunisation schedule: 0, 1 & 6 mth. Accelerated schedule: 0, 1 & 2 mth followed by 4th dose at 12 mth.
Adult ≥20 yr requiring rapid induction of protection eg, person travelling to areas of high endemicity & who commence a course of vaccination against hepatitis B w/in 1 mth prior to departure 20 mcg at 0, 7, 21 days followed by 4th dose at 12 mth after 1st dose.
Childn ≤19 yr, infant & neonate born of HBV-carrier mother 10 mcg at 0, 1, 2 & 12 mth, or at 0, 1 & 6 mth.
Patients 11-15 yr 20 mcg as 2-dose course (0 & 6 mth) for patients w/ low risk of hepatitis B infection, or 10 mcg as 3-dose or accelerated schedule for patients undergoing haemodialysis, travelers to endemic regions & close contacts of infected subjects.
Renal insufficiency including patients undergoing haemodialysis ≥16 yr Two 20 mcg at 1, 2 & 6 mth from 1st dose,
≤15 yr including neonates 10 mcg at 0, 1, 2 & 12 mth, or at 0, 1 & 6 mth.
Known or presumed HBV exposure Administer 1st dose simultaneously w/ hepatitis B Ig at separate inj site at 0, 1, 2-12 mth.
Haemodialysis & other immunocompromised patient Recommended for booster dose.
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