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The dose is one drop of COSOPT/COSOPT-S in the affected eye(s) two times daily.
When substituting COSOPT/COSOPT-S for another ophthalmic antiglaucoma agent(s), discontinue the other agent(s) after proper dosing on one day, and start COSOPT/COSOPT-S on the next day.
If another topical ophthalmic agent is being used, COSOPT/COSOPT-S and the other agent should be administered at least ten minutes apart.
Safety and efficacy in pediatric patients below the age of 2 years have not been established (For information regarding use in pediatric patients ≥2 years of age see section VIII).
When using nasolacrimal occlusion or closing the eyelids for 2 minutes, the systemic absorption is reduced. This may result in an increase in local activity.
