IM/IV Adult 2-4 g daily every 12 hr in equally divided doses. Severe or refractory infection May be increased up to 8 g daily every 12 hr in equally divided doses. Childn 40-80 mg/kg daily every 6-12 hr in equally divided doses. Severe or refractory infection May be increased up to 160 mg/kg daily in 2-4 equally divided doses.
Not to be used in hypersensitive patients. Discontinue & institute appropriate therapy if skin rash, irritation or edema occurs. Penicillin-sensitive patients. Vit K deficiency; overgrowth of non-susceptible organisms in prolonged use. Patients w/ poor diet, malabsorption states (eg, cystic fibrosis), on prolonged IV alimentation regimens & receiving anticoagulant. Monitor prothrombin time & administer exogenous vit K. Periodically check for organ system dysfunction including renal, hepatic & hematopoietic systems during extended therapy. Severe biliary obstruction & hepatic disease. Renal impairment. Pregnancy & lactation. Premature infants or neonates.
J01DD62 - cefoperazone and beta-lactamase inhibitor ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.
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