Postpone vaccination in patients suffering from acute severe febrile illness. Not to be administered IV. Patients w/ thrombocytopenia or bleeding disorder. Immunosuppressed patients. History or family history of convulsions & adverse event following DPT vaccination. Syncope. Perform review of medical history & clinical exam before vaccination. Carefully consider giving doses of pertussis-containing vaccines for temp ≥40°C w/in 48 hr of vaccination, not due to another identifiable cause; collapse or shock-like state (hypotonic-hyporesponsiveness episode) w/in 48 hr of vaccination; persistent, inconsolable crying lasting ≥3 hr, occurring w/in 48 hr of vaccination; convulsions w/ or w/o fever, occurring w/in 2-3 days of vaccination. Defer pertussis immunization in childn w/ progressive neurological disorders including infantile spasms, uncontrolled epilepsy or progressive encephalopathy. Lactation.
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