Aminoleban

Aminoleban

Manufacturer:

Otsuka

Distributor:

Zuellig Pharma

Marketer:

Thai Otsuka
Concise Prescribing Info
Contents
Per 500 mL L-threonine 2.25 g, L-serine 2.50 g, L-proline 4 g, L-cysteine HCl·H2O 0.20 g (L-cysteine equiv 0.15 g), aminoacetic acid 4.50 g, L-alanine 3.75 g, L-valine 4.20 g, L-methionine 0.50 g, L-isoleucine 4.50 g, L-leucine 5.50 g, L-phenylalanine 0.50 g, L-tryptophan 0.35 g, L-histidine HCl·H2O 1.60 g (L-histidine equiv 1.20 g), lysine HCl 3.80 g, (L-lysine equiv 3.05 g), L-arginine HCl 3.65 g, (L-arginine equiv 3 g). Amino acids 7.99% w/v, branched-chain amino acid 35.5% w/w, total nitrogen 12.2 g/L, Cl approx 94 mEq/L, Na approx 12 mEq/L
Indications/Uses
Hepatic encephalopathy in patients w/ chronic liver disease.
Dosage/Direction for Use
Adult 500-1,000 mL/dose by IV drip infusion. Peripheral infusion rate: 500 mL over 180-300 min (approx 25-40 drops/min). TPN 500-1,000 mL of inj combined w/ dextrose or other soln, administered over 24 hr via the central vein.
Contraindications
Severe renal disorder. Abnormal amino acid metabolism.
Special Precautions
Administer slowly via a peripheral vein. Discontinue administration or use an alternate site if vascular pain occurs. Patients w/ severe acidosis; CHF. Carefully monitor electrolyte balance in concomitant use w/ electrolyte soln or a large dose. Childn. Elderly.
Adverse Reactions
Hypoglycemia, hyperammonemia. Nausea, vomiting; chest discomfort & palpitation; transient increase in blood ammonia conc; acidosis (large dose); chills, fever, headache, vascular pain.
MIMS Class
Parenteral Nutritional Products
ATC Classification
B05BA01 - amino acids ; Belongs to the class of solutions for parenteral nutrition used in I.V. solutions.
Presentation/Packing
Form
Aminoleban soln for inj
Packing/Price
500 mL x 10 × 1's
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