Albutein Dosage/Direction for Use

Albutein 5%, 20% and 25% is administered intravenously. The total dosage will vary with the individual. In adults, an initial infusion of 500 mL is suggested (for 5%) or 100 mL is suggested (for 20% and 25%). Additional amounts may be administered as clinically indicated.
In the treatment of the patient in shock with greatly reduced blood volume, Albutein 5%, 20% and 25% may be administered as rapidly as necessary in order to improve the clinical condition and restore normal blood volume. This may be repeated in 15-30 minutes if the initial dose fails to prove adequate. In the patient with a slightly low or normal blood volume, the rate of administration should be 1-2 mL per minute (for 5%), or 1 mL per minute (for 20% and 25%).
20% and 25%: If dilution of Albutein 20% and 25% is clinically desirable, compatible diluents include sterile 0.9% Sodium Chloride solution or sterile 5% Dextrose in Water.
Pediatric Use: The pediatric use of Albutein 5%, 20% and 25% have not been clinically evaluated. The dosage will vary with the clinical state and body weight of the individual. Typically, a dose one-quarter to one-half the adult dose may be administered, or dosage may be calculated on the basis of 0.6 to 1.0 gram per kilogram of body weight (12 to 20 mL of Albutein 5%), (3 to 5 mL of Albutein 20%) and (2.4 to 4 mL of Albutein 25%). For jaundiced infants suffering from hemolytic disease of the newborn, the appropriate dose for binding of free serum bilirubin is 1 gram per kilogram of body weight which may be administered during the procedure (for 20% and 25% only). The usual rate of administration in children should be one-quarter the adult rate.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
DIRECTIONS FOR USE: 5%: (250 mL and 500 mL).
20% and 25%: (50 mL and 100 mL).
When an Administration Set is Used: Flip off plastic cap on top of the vial and expose rubber stopper. Cleanse exposed rubber stopper with suitable germicidal solution, being sure to remove any excess. Observe aseptic technique and prepare sterile intravenous equipment as follows: 1. Close clamp on administration set.
2. With bottle upright, squeeze drip chamber, thrust piercing pin straight through stopper center. Do not twist or angle.
3. Immediately invert bottle, release drip chamber to automatically establish proper fluid level in drip chamber (half full).
4. Attach infusion set to administration set, open clamp and allow solution to expel air from tubing and needle, then close clamp.
5. Make venipuncture and adjust flow.
6. Discard all administration equipment after use. Discard any unused contents.
When an Administration Set is Not Used: Flip off plastic cap on top of the vial and expose rubber stopper. Cleanse exposed rubber stopper with suitable germicidal solution, being sure to remove any excess. Observe aseptic technique and prepare sterile intravenous equipment as follows: 1. Using aseptic technique, attach filter needle to a sterile disposable plastic syringe.
2. Insert filter needle into Albutein 5%, 20% or 25%.
3. Aspirate Albutein 5%, 20% or 25% from the vial into the syringe.
4. Remove and discard the filter needle from the syringe.
5. Attach desired size needle to syringe.
6. Discard all administration equipment after use. Discard any unused contents.