History of allergic reaction to painkillers. Not to be taken w/ alcohol; other paracetamol-containing medicines. Underwt or malnourished. Patients regularly drinking alcohol. Discontinue use if the patient experiences allergic reactions; potential serious skin reactions; previously experienced breathing problems w/ aspirin or NSAIDs; nausea, sudden wt loss, appetite loss & yellowing of eyes & skin; unexplained bruising or bleeding; mouth ulcers. May increase risk of metabolic acidosis if the patient has severe infection. Concomitant use w/ warfarin or similar blood thinners; flucloxacillin. Liver or kidney disease; history of liver or kidney disease. Pregnancy & lactation. Not recommended for childn <12 yr.