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Effect on ability to drive or operate machinery: As patients may experience faintness and/or dizziness, particularly the elderly, reaction time when driving or operating machinery may be impaired especially at the start of treatment.
Interaction with other drugs: Concomitant use of alcohol may enhance vascular effects.
Concomitant use with other nitrates: If a patient is already using glyceryl trinitrate or other nitrates for Cardiac disease then using Rectogesic could potentially cause tachyphylaxis by eliminating the night time free interval.
Where such tachyphylaxis may cause concern it is advised that Rectogesic should be used during the day only.
Use in children: The safety and effectiveness of glyceryl trinitrate in children have not been established.
