Picoprep Dosage/Direction for Use

Posology: Directions for reconstitution: Reconstitute the PICOPREP powder right before each administration. Do not prepare the solution in advance. Reconstitute the contents of one sachet in a cup of water (approximately 150 ml). Stir for 2-3 minutes, the solution should now become an off-white, cloudy liquid with a faint odour of orange. Drink the solution. If it becomes warm, wait until it cools sufficiently to drink.
Adults (including the elderly): (if the procedure is scheduled for the afternoon, it is recommended that the Split-Dose regimen should be used): Split-Dose Regimen (evening-before and day of the procedure): The first PICOPREP sachet is taken the night before the procedure, and the second is taken the next day, in the morning prior to the procedure.
On the day before the procedure - 1 sachet: The first reconstituted sachet is taken in the evening (e.g. 5:00 to 9:00 PM), followed by at least five 250 ml drinks of clear liquids, spread over several hours.
On the day of the procedure - 1 sachet: The second reconstituted sachet is taken in the morning (5-9 hours before the procedure), followed by at least three 250 ml drinks of clear liquids, spread over several hours.
Clear liquids may be consumed until 2 hours before the time of the procedure or;
Day-Before Regimen (evening-before the procedure only): The first PICOPREP sachet is taken in the afternoon or early evening and the second is taken approximately 6 hours later, the night before the procedure.
On the day before the procedure - 2 sachets: The first reconstituted sachet is taken in the afternoon or early evening (e.g. 4:00 to 6:00 PM), followed by at least five 250 ml drinks of clear liquids, spread over several hours.
The second reconstituted sachet is taken in the late evening (e.g., 10:00 PM to 12:00 AM), followed by at least three 250 ml drinks of clear liquids, spread over several hours.
Clear liquids may be consumed until 2 hours before the time of the procedure.
Paediatric population: The safety and efficacy of PICOPREP in paediatric patients has not been established.