Hypersensitivity to any of the ingredients of the product; Congestive cardiac failure; Gastric retention; Gastro-intestinal ulceration; Toxic colitis; Toxic megacolon; Ileus; Nausea and vomiting; Acute surgical abdominal conditions such as acute appendicitis; Known or suspected gastro-intestinal obstruction or perforation; Severe dehydration; Rhabdomyolysis; Hypermagnesemia; Active inflammatory bowel disease; In patients with severely reduced renal function, accumulation of magnesium in plasma may occur. Another preparation should be used in such cases.