Prevention of gastric & duodenal ulcer recurrences associated w/ low-dose aspirin therapy Adult/elderly Usual dose: 5 mg once daily, may be increased to 10 mg once daily.
Active duodenal & benign gastric ulcer, & erosive or ulcerative GERD Usual dose: 10 mg once daily, may be increased up to 20 mg once daily depending on severity of symptoms. Duration of treatment: Up to 8 wk for active benign gastric ulcer & symptomatic erosive or ulcerative GERD; 6 wk for active duodenal ulcer.
Reflux esophagitis patient who do not respond to usual doses of proton pump inhibitor treatment 10 mg bd for a further 8 wk.
Patient w/ severe mucosa injury 20 mg bd.
GERD long-term management maintenance 10 or 20 mg once daily.
Maintenance therapy of reflux esophagitis when proton pump inhibitor treatment is ineffective May administer 10 mg bd.
Symptomatic treatment of moderate to very severe GERD 10 mg once daily in patients w/o esophagitis. Further investigate if symptom control is not achieved in 4 wk. Once symptoms are resolved, achieve subsequent symptom control using on-demand regimen w/ 10 mg once daily.
H. pylori eradication Pariet 20 mg bd + clarithromycin 500 mg bd & amoxicillin 1 g bd. Duration of treatment: 7 days.
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