When applied topically, particularly to large areas, when the skin is broken, or under occlusive dressings, corticosteroid may be absorbed in sufficient amounts to cause systemic effects. Discontinue use if local reactions develop. Review treatment in 7 days is required if significant regeneration or repair of oral tissues has not occurred. Normal body responses decreased in patients receiving topical corticosteroid therapy. Patients with TB, peptic ulcer or diabetes mellitus should not be treated with any corticosteroid preparation without the advice of the patient's physician. Visual disturbance may be reported with systemic and topical corticosteroid use. If a patient presents with symptoms such as blurred vision or other visual disturbances, the patients should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma, or rare diseases such as central serous chorioretinopathy (CSCR) which have been reported after use of systemic and topical corticosteroids.