Olmetec Description

Olmetec is available for oral use as film-coated tablets containing 20 mg, or 40 mg of olmesartan medoxomil.
Olmesartan medoxomil is a prodrug, which is hydrolysed to the active metabolite olmesartan during absorption from the gastrointestinal tract. Olmesartan is a selective AT₁ subtype angiotensin II receptor antagonist.
Olmesartan medoxomil is described chemically as (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1[[2'-1H-tetrazol-5-yl]-1,1'biphenyl-4-yl]methyl]1H-imidazol-5-carboxylate. Alternatively, it can be described as "2,3-dihydroxy-2-butenyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5-carboxylate, cyclic 2,3-carbonate".
Its empirical formula is C₂₉H₃₀N₆O₆.
Olmesartan medoxomil is a white to light yellowish-white powder or crystalline powder with a molecular weight of 558.59. It is practically insoluble in water and sparingly soluble in methanol.
Excipients/Inactive Ingredients: The inactive ingredients in olmesartan medoxomil tablets comprise: microcrystalline cellulose, low substituted hydroxypropylcellulose, lactose, hydroxypropylcellulose and magnesium stearate.
In those countries where the tablets are film-coated, the film coat contains the following ingredients: talc, titanium dioxide, hypromellose.