Nicorette Overdosage

Nicorette Invisi Transdermal Patch & Nicorette Icy Mint Medicated Chewing Gum: Symptoms of overdose with nicotine from Nicorette Invisi Transdermal Patch/Nicorette Icy Mint Gum may occur in smokers who have previously had a low nicotine intake from cigarettes or if other sources of nicotine are used concomitantly with Nicorette Invisi Transdermal Patch/Nicorette Icy Mint Gum.
Acute or chronic toxicity of nicotine in man is highly dependent on mode and route of administration. Adaptation to nicotine (e.g. in smokers) is known to significantly increase tolerability compared with non-smokers. The acute minimum lethal oral dose of nicotine is believed to be 40 to 60 mg in children (oral intake of tobacco from cigarettes) or 0.8 to 1.0 mg/kg in adult non-smokers.
Symptoms of overdose are those of acute nicotine poisoning and include nausea, vomiting, increased salivation, abdominal pain, diarrhoea, sweating, headache, dizziness, disturbed hearing and marked weakness. At high doses, these symptoms may be followed by hypotension, weak and irregular pulse, breathing difficulties, prostration, circulatory collapse and general convulsions.
Doses of nicotine that are tolerated by adult smokers during treatment may produce severe symptoms of poisoning in children and may prove fatal. Suspected nicotine poisoning in a child should be considered a medical emergency and treated immediately.
Management of overdose: Administration of nicotine must be stopped immediately and the patient should be treated symptomatically.
In the event of overdose, get medical help right away.
Nicorette Invisi Transdermal Patch: Remove patch and rinse application site with water.
Nicorette Icy Mint Medicated Chewing Gum: The risk of poisoning as a result of swallowing the gum is very small, as absorption in the absence of chewing is slow and incomplete.
If excessive amount of nicotine is swallowed, activated charcoal reduces the gastrointestinal absorption of nicotine.
Nicorette QuickMist Mouth Spray: If the patient uses more Nicorette QuickMist than they should: Overdosing of nicotine may occur if the patient smokes at the same time as they take Nicorette QuickMist.
If a child takes Nicorette QuickMist or if the patient has used more Nicorette QuickMist than they should, contact a doctor or go to nearest hospital immediately. Doses of nicotine that are tolerated by adult smokers during treatment may produce severe symptoms of poisoning in small children and may prove fatal.
The symptoms of overdose are feeling sick (nausea), too much saliva, stomach pain, diarrhoea, sweating, headache, dizziness, changed hearing, and feeling very weak. At high doses, these symptoms may be followed by low blood pressure, weak and irregular pulse, difficulty breathing, extreme tiredness, circulatory collapse and general convulsions.
Administration of nicotine should be stopped temporarily if any symptoms of nicotine excess occur. Nicotine intake should be decreased by either lowering dosing frequency or strength if nicotine excess symptoms persist.
If the patient has any further questions on the use of the product, ask a doctor or pharmacist.