Occasionally, burning or dryness of the nasal mucosa, sneezing. In rare cases - after the effect has worn off – an intense sensation of "blocked" nose (reactive hyperaemia). With topical intranasal use, overdosage leads occasionally to systemic sympathomimetic effects like palpitations, accelerated pulse (tachycardia) and increase in blood pressure. Restlessness, insomnia, tiredness and headaches have been observed in very rare cases. Epistaxis, apnoea in newborns and in young infants (esp. in case of overdosage), hallucinations and convulsions.
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