Hexaxim Contraindications

History of an anaphylactic reaction after a previous administration of Hexaxim.
Hypersensitivity to the active substances, to any of the excipients listed in Description, to trace residuals (glutaraldehyde, formaldehyde, neomycin, streptomycin and polymyxin B), to any pertussis vaccine, or after previous administration of Hexaxim or a vaccine containing the same components or constituents.
Vaccination with Hexaxim is contraindicated if the individual has experienced an encephalopathy of unknown aetiology, occurring within 7 days following prior vaccination with a pertussis containing vaccine (whole cell or acellular pertussis vaccines).
In these circumstances pertussis vaccination should be discontinued and the vaccination course should be continued with diphtheria, tetanus, hepatitis B, poliomyelitis and Hib vaccines.
Pertussis vaccine should not be administered to individuals with progressive neurologic disorder, uncontrolled epilepsy or progressive encephalopathy until treatment for the condition has been established, the condition has stabilised and the benefit clearly outweighs the risk.