Neutropenia, leukopenia, anaemia; decreased appetite; peripheral neuropathy, headache; dyspnoea, cough; nausea, constipation, diarrhoea, vomiting; alopecia; arthralgia & myalgia, back pain, pain in extremity; fatigue/asthenia, pyrexia; decreased wt. UTI, pneumonia, oral candidiasis & herpes, upper resp tract infection, nasopharyngitis, rhinitis, herpes zoster; lymphopenia, febrile neutropenia, thrombocytopenia; hypokalaemia, hypomagnesaemia, dehydration, hyperglycaemia, hypophosphataemia, hypocalcaemia; insomnia, depression; dysgeusia, dizziness, hypoaesthesia, lethargy, neurotoxicity; increased lacrimation, conjunctivitis; vertigo, tinnitus; tachycardia; hot flush, pulmonary embolism; oropharyngeal pain, epistaxis, rhinorrhoea; abdominal pain, stomatitis, dry mouth, dyspepsia, GERD, abdominal distension; increased AST, ALT, γ-glutamyl transferase, hyperbilirubinaemia; rash, pruritus, nail disorder, night sweats, dry skin, erythema, hyperhidrosis, palmar plantar erythrodysaesthesia; bone, musculoskeletal & chest pain, muscle spasms, muscular weakness; dysuria; mucosal inflammation, peripheral oedema, pain, chills, chest pain, influenza-like illness.