Pharmacology: Pharmacodynamics: Hydrocortisone is a topically active corticosteroid which has anti-inflammatory, antipruritic and vasoconstrictive actions.
Pharmacokinetics: Corticosteroids are extensively bound to plasma protein. Only unbound corticosteroids has pharmacological effects or is metabolised. They are metabolised mainly in the liver and also in the kidney, and are excreted in the urine.