IV Breast cancer 1,250 mg/m
2 over 30 min infusion on days 1 & 8 of each 21-day cycle. Administer paclitaxel 175 mg/m
2 on day 1 as a 3-hr infusion prior to gemcitabine inj.
Non-small cell lung cancer 4-wk schedule: 1,000 mg/m
2 over 30 min infusion on days 1, 8 & 15 of each 28-day cycle, administer cisplatin 100 mg/m
2 on day 1 after gemcitabine infusion. 3-wk schedule: 1,250 mg/m
2 over 30 min infusion on days 1 & 8 of each 21-day cycle, administer cisplatin 100 mg/m
2 on day 1 after gemcitabine infusion.
Pancreatic cancer 1,000 mg/m
2 over 30 min infusion once wkly for up to 7 wk (or until toxicity necessitates reducing or holding a dose), followed by a wk of rest from treatment. Subsequent cycles should consist of infusions once wkly for 3 consecutive wk out of every 4 wk.