Euthyrox Dosage/Direction for Use

In order to treat each patient according to his/her individual needs, tablets are available with a levothyroxine sodium content ranging from 25 - 200 microgram. Patients therefore usually need to take only one tablet per day.
The dosage recommendations given are only for guidance. Determination of the individual daily dose on the basis of laboratory tests and clinical examinations is recommended.
In children with a sound heart, and for neonates where rapid replacement is important, the entire dose may be started. In adults, initiation of thyroid hormone therapy at low dose is recommended. The dose may be increased gradually every 2 - 4 weeks until the full replacement dose is reached.
In elderly patients, in patients with coronary heart disease, and in patients with severe or long-existing hypothyroidism, special caution is required when initiating therapy with thyroid hormones: Treatment is initiated at a low dose, which is increased slowly and at lengthy intervals with frequent monitoring of thyroid hormones. A maintenance dose lower than that required for complete correction of TSH levels may be considered.
Experience has shown that a lower dose is sufficient in low-weight patients and in patients with a large nodular goitre. (See Table 1.)

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Applies only to tablets of 100 microgram: (See Table 2.)

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Administration: The daily doses can be given in a single administration.
Ingestion: as a single daily dose in the morning on an empty stomach, half an hour before breakfast, preferably with a little liquid (for example, half a glass of water).
Infants receive the entire dose at once at least 30 minutes before the first meal of the day.
Tablets are suspended in some water and the resultant suspension is administered with some more liquid. The suspension must be prepared freshly prior to each administration.
Duration of treatment: In the case of substitution in hypothyroidism and after strumectomy or thyroidectomy as well as for relapse prophylaxis after euthyroid goitre removal treatment is usually continued for lifespan.
Concomitant therapy of hyperthyroidism after achieving euthyroid status is indicated for the period in which the anti-thyroid agent is given.
For benign euthyroid goitre, treatment duration is for some months up to lifespan. If the medical treatment was not sufficient within this time, surgery or radioiodine therapy of the goitre should be considered.