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Pregnancy: Estelle-35 is not indicated during pregnancy. If pregnancy occurs during treatment with Estelle-35, further intake must be stopped (see Pharmacology: Toxicology: "Preclinical safety data" under Actions).
Lactation: The administration of Estelle-35 is contraindicated during lactation. Cyproterone acetate is transferred into the milk of lactating women. About 0.2% of the maternal dose will reach the newborn via milk corresponding to a dose of about 1 μg/kg. 0.02% of the daily maternal dose of ethinylestradiol could be transferred to the newborn via milk during established lactation.
