Estelle-35 Contraindications

Preparations containing estrogen/progestogen combinations should not be used in the presence of any of the conditions listed as follows. Should any of the conditions appear for the first time during their use, the product should be stopped immediately.
Concomitant use with another hormonal contraceptive (see 'Indications').
Presence or a history of venous or arterial thrombotic/thromboembolic events (e.g. deep venous thrombosis, pulmonary embolism, myocardial infarction) or of a cerebrovascular accident.
Presence or a history of prodromi of a thrombosis (e.g. transient ischaemic attack, angina pectoris).
Presence or history of cerebrovascular accident.
History of migraine with focal neurological symptoms.
The presence of a severe or multiple risk factor(s) for venous or arterial thrombosis may also constitute a contraindication (see 'Precautions') such as: Diabetes mellitus with vascular symptoms, Severe hypertension, Severe dyslipoproteinaemia.
Hereditary or acquired predisposition for venous or arterial thrombosis, such as activated protein C (APC) resistance, antithrombin-III-deficiency, protein C deficiency, protein S deficiency, hyperhomocysteinaemia and antiphospholipid-antibodies (anticardiolipin-antibodies, lupus anticoagulant).
Severe hepatic disease as long as liver function values have not returned to normal.
Presence or history of liver tumours (benign or malignant).
Known or suspected sex-steroid influenced malignancies (e.g. of the genital organs or the breasts).
Undiagnosed vaginal bleeding.
Known or suspected pregnancy.
Lactation.
Hypersensitivity to the active substances or to any of the excipients.
Estelle-35 is not for use in men.
Jaundice or persistent itching during a previous pregnancy, Dubin Johnson syndrome. Rotor syndrome, sickle cell anaemia existing or treated cancer of the breast or the endometrium, disturbances of lipometabolism, a history of herpes of pregnancy, otosclerosis with deterioration during pregnancy.