Discontinue treatment if MI, cerebrovascular disorders, arterial or venous thromboembolism (venous thromboembolism or pulmonary embolism), thrombophlebitis or retinal thrombosis are suspected. Mild to moderate hepatic dysfunction. History of depression. Epilepsy, migraine, asthma, cardiac or renal dysfunction; diabetes. May increase the risk of retinal vascular lesions. Terminate use in case of transient ischemic events, appearance of sudden severe headaches, or vision impairments related to papillary edema or retinal hemorrhage. Abrupt discontinuation may cause increased anxiety, moodiness & increased sensibility to seizures. Impaired liver or renal function. May affect the ability to drive or operate machinery. Pregnancy & lactation.