Not for ophthalmic use. In the first trimester of pregnancy, econazole should only be used when considered essential to the welfare of the patient. It is not known whether econazole is excreted in breast milk or whether it has a harmful effect in the newborn. Appropriate treatment should be given in the presence of infections. If there is no favourable response, treatment with the corticosteroid should be discontinued until the infection has been controlled. Corticosteroid applied to large areas of the skin can be absorbed in sufficient amount to produce systemic effects like adrenal suppression, manifestation of Cushing's syndrome, hyperglycaemia and glucosuria in some patients. Thus suitable precautions should be taken during prolonged treatment, when treating extensive body surface area, when using the occlusive technique and when treating children (because of a larger skin surface area to body weight ratio). Suitable precautions should also be taken when treating lesions complicated with stasis dermatitis or impaired circulation. Discontinue use if irritation, sensitivity or other reactions develop and institute appropriate treatment.
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