Hypersensitivity to active substance levofloxacin or to other quinolones, to dexamethasone, or to other steroids, or to any of the excipients listed in Description; Herpes simplex keratitis, varicella and other viral disease of the cornea and conjunctiva; Mycobacterial infections of the eye caused by, but not limited to, acid-fast bacilli such as Mycobacterium tuberculosis, Mycobacterium leprae, or Mycobacterium avium; Fungal diseases of ocular structures; Untreated purulent infection of the eye.