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Patients who are hypersensitive to Apo-Anastrozole (anastrozole) or to any ingredient in the formulation.
Premenopausal women.
Pregnant or lactating women.
Patients with severe renal impairment (creatinine clearance less than 20 ml/min).
Patients with moderate or severe hepatic disease.
Oestrogen-containing therapies should not be co-administered with anastrozole as they would negate its pharmacological action.
Concurrent tamoxifen therapy (see Interactions).
