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Apo-Amitriptyline

Apo-Amitriptyline

amitriptyline

Manufacturer:

Apotex

Distributor:

Pharmaforte
Concise Prescribing Info
Contents
Amitriptyline
Indications/Uses
Depression, including that accompanied by anxiety.
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Dosage/Direction for Use
Initially 75-150 mg daily in divided doses. Maintenance: 25-100 mg daily in divided doses. Hospitalized patient 100 mg/day initially & gradually increased to 200-300 mg/day. Adolescent & elderly patient Initially 20-30 mg/day in divided doses w/ gradual increments.
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Overdosage
View Apo-Amitriptyline overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Immediate recovery phase after MI, heart block. Mania. Patients receiving MAOIs. Acute CHF.
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Special Precautions
CV diseases. Hyperthyroidism. Hepatic impairment. History of epilepsy, suicidal tendencies. Narrow-angle glaucoma, urinary retention, prostatic hypertrophy. Diabetes. Elderly, childn <5 yr.
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Adverse Reactions
Dry mouth, constipation, urinary retention, blurred vision, narrow-angle glaucoma, impotence, drowsiness, dizziness, sweating, weakness, fatigue, epileptiform seizures, orthostatic hypotension, palpitation, tachycardia, cardiac arrhythmia, extrapyramidal symptoms, endocrine effects.
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Drug Interactions
Barbiturates, phenytoin, carbamazepine, phenothiazines, cimetidine, estrogen, OC, alcohol, sympathomimetic amines, debrisoquine, guanethidine, clonidine, bethanidine.
Description
View Apo-Amitriptyline description for details of the chemical structure and excipients (inactive components).
Action
View Apo-Amitriptyline mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Antidepressants
ATC Classification
N06AA09 - amitriptyline ; Belongs to the class of non-selective monoamine reuptake inhibitors. Used in the management of depression.
Presentation/Packing
Form
Apo-Amitriptyline tab 10 mg
Packing/Price
1000's
Form
Apo-Amitriptyline tab 25 mg
Packing/Price
1000's
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