Zyphrine Special Precautions

The administration of Levocetirizine to infants and toddlers aged less than 2 years is not recommended.
Precaution is recommended with intake of alcohol.
At therapeutic doses, no clinically significant interactions have been demonstrated with alcohol (for a blood alcohol level of 0.5 g/L). Nevertheless, precaution is recommended if alcohol is taken concomitantly. Caution in epileptic patients and patients at risk of convulsions are recommended.
Patients should be cautioned against engaging hazardous occupations requiring complete mental awareness, and motor coordination such as operating machinery or driving a motor vehicle after ingestion of Levocetirizine hydrochloride. Concurrent use with alcohol or other CNS depressants should be avoided. Levocetirizine hydrochloride should be used with caution in patients with predisposing factors of urinary retention (e.g. spinal cord lesion, prostatic hyperplasia) as drug may increase the risk of urinary retention. Discontinue product if urinary retention occurs.