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Zolid: Patients with known hypersensitivity to thiazolidinediones or any components of Zolid.
ZolidPlus: Hypersensitivity to pioglitazone, metformin HCl or any component of ZolidPlus.
Cardiac failure or history of cardiac failure (NYHA class III or IV); hepatic impairment or evidence of active liver disease; acute or chronic disease which may cause tissue hypoxia eg, cardiac or respiratory failure, recent myocardial infarction, shock; acute alcohol intoxication, alcoholism; renal failure or dysfunction (creatinine clearance <60 mL/min), which may also result from conditions eg, cardiovascular collapse (shock), acute myocardial infarction and septicemia.
