Xtenda Adverse Reactions

Ceftriaxone is generally well tolerated. However the following adverse reactions, which were considered to be related to Ceftriaxone therapy or of uncertain etiology, were observed: Local Reactions: Pain, induration and tenderness. Phlebitis was reported after I.V. administration. The incidence of injection site reaction after I.M. administration was reported.
Hypersensitivity: Rash, less frequently reported were pruritus, fever or chills.
Hematologic: Thrombocytosis and leukopenia, Less frequently reported were anemia, hemolytic anemia, neutropenia, lymphopenia, thrombocytopenia and prolongation of the prothrombin time.
Gastrointestinal: Diarrhea, less frequently reported were nausea or vomiting, and dysgeusia. The onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment.
Hepatic: Elevations of SGOT or SGPT. Less frequently reported were elevations of alkaline phosphatase and bilirubin.
Renal: Elevations of the BUN. Less frequently reported were elevations of creatinine and the presence of casts in the urine.
Central Nervous System: Headache or dizziness were reported occasionally.
Genitourinary: Moniliasis or vaginitis were reported occasionally.
Miscellaneous: Diaphoresis and flushing were reported occasionally.
Other rarely observed reactions include leukocytosis, lymphocytosis, monocytosis, basophilia, a decrease in the prothrombin time, jaundice, gall bladder sludge, glycosuria, hematuria, anaphylactic shock, palpitations and epistaxis.