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Tusedex

Tusedex

Manufacturer:

Medhaus

Distributor:

Medhaus
Concise Prescribing Info
Contents
Paracetamol 325 mg, phenylephrine HCl 25 mg, dextromethorphan HBr 10 mg
Indications/Uses
Relief of cough, clogged nose, postnasal drip, headache, body aches & fever associated w/ the common cold, allergic rhinitis, sinusitis, flu, & other minor resp tract infections. Helps decongest sinus openings & passages.
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Dosage/Direction for Use
Adult 1 cap every 6 hr.
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Overdosage
View Tusedex overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to paracetamol, phenylephrine HCl or dextromethorphan HBr. High BP or severe heart disease. Anemia. Kidney or liver disease. Pregnancy & lactation.
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Special Precautions
Risk of resp failure (eg, chronic bronchitis, emphysema or during asthma attack), persistent or chronic cough lasting for >3 wk or cough accompanied by excessive secretions. High BP or heart problems, glaucoma, thyroid problems, diabetes, liver or kidney disease, enlarged prostate, bladder problems or difficulty in urinating. Discontinue if fever gets worse or lasts >3 days or new symptoms occur. Concomitant use w/ warfarin. May impair ability to drive or operate machinery.
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Adverse Reactions
Hypersensitivity. Phenylpropanolamine: Sudden severe headache, nervousness, restlessness, insomnia/sleep disturbance, dizziness, anxiety, confusion, high BP, palpitation, chest tightness, tremor, agitation, irritability, aggressiveness (particularly in young childn), nausea & blurred vision. Paracetamol: Skin rashes, changes in the number of WBC & platelets; minor stomach & intestinal disturbances.
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Drug Interactions
Increased toxicity w/ sympathomimetic agents (eg, epinephrine) & general anesth (eg, halothane). May result in hypertensive crisis w/ MAOIs (eg, selegiline, moclobemide) & antidepressants (eg, amitriptylline, imipramine). Paracetamol: May increase INR w/ warfarin. May increase susceptibility to the harmful effects of liver w/ medicines for convulsions (eg, phenobarb, phenytoin). May accelerate absorption w/ metoclopramide or domperidone. May reduce absorption w/ cholestyramine. Phenylpropanolamine: May produce additive increase in BP w/ caffeine. Dextromethorphan: CYP450 isoenzyme CYP2D6 inhibitors eg, amiodarone, haloperidol, quinidine, SSRIs & thioridazine. Symptoms of toxicity w/ amiodarone & quinidine. Additive CNS depression w/ alcohol, antihistamines, psychotropics & other CNS depressants.
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Storage
View Tusedex storage conditions for details to ensure optimal shelf-life.
Action
View Tusedex mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Cough & Cold Preparations
ATC Classification
N02BE51 - paracetamol, combinations excl. psycholeptics ; Belongs to the class of anilide preparations. Used to relieve pain and fever.
Presentation/Packing
Form
Tusedex cap
Packing/Price
100's (P800/pack)
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