Patients with known shock to this drug.
Patients with known hypersensitivity to the cephalosporin group of antibiotics.
The drug should be administered with caution in the following patients:
Patients with a history of hypersensitivity to the drug or cephalosporin antibiotics, but if necessary, the drug can be given with caution.
Patients with a history of hypersensitivity to penicillin-group antibiotics or β-lactam antibiotics.
Patients whose family are susceptible to cause the allergic symptoms such as bronchial asthma, eruption and urticaria, etc.
Patients with severe renal disorder.
Patients who cannot ingest orally, or parenteral patients, elderly patients, patients with systemic bad condition (because avitaminosis K may occur, they should be sufficiently observed).