Rosuvastatin is given in an initial dose of 5 to 10 mg or as prescribed by the physician. Increased if necessary after not less than 4 weeks to 20 mg once daily; increased after a further 4 weeks to 40 mg only in severe hypercholesterolemia with high cardiovascular risk and under specialist supervision. Maximum of 20 mg daily with concomitant ciclosporin or fibrate.
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