Riliz Dosage/Direction for Use

General Dosing Recommendations: Dienogest tablets are intended for continuous administration in women for the treatment of endometriosis. There are reported long-term studies of dienogest use for more than 15 months.
Drug administration can be started on any day of the menstrual cycle.
May be taken with or without food.
Recommended Dose and Dose Adjustment: Adults: Orally, 1 tablet daily without a break, preferably at the same time each day, with some liquid as needed.
Tablets must be taken continuously regardless of any vaginal bleeding.
When a pack is finished, the next one should be started without interruption.
Or, as prescribed by a physician.
Missed Dose: The efficacy of dienogest may be reduced in the event of missed tablets, vomiting and/or diarrhea (if occurring within 3 to 4 hours after the tablet is taken). In the event of a missed dose, the patient should take 1 tablet only as soon as possible and then continue to take the next tablet at her usual time the next day. A tablet not absorbed due to vomiting or diarrhea should likewise be replaced by 1 tablet. The patient should not take more than 1 tablet per day.
Dosage in Patients with Hepatic Impairment: Dienogest is contraindicated in patients with existing or history of hepatic disease.
Dosage in Patients with Renal Impairment: No dosage adjustment is necessary in patients with renal impairment.