SCChildn 12 mth-12 yr single dose. 6 to ≤12 mth if 1st dose is given at this age, 2nd dose should be administered at 12 mth or later. Administer as SC inj in the deltoid region of the upper arm or in the higher anterolateral area of the thigh.
View Proquad overdosage for action to be taken in the event of an overdose.
Contraindications
Hypersensitivity to any component of the vaccine including gelatin. History of anaphylactoid reaction to neomycin. Blood dyscrasias, leukemia, lymphomas of any type, or other malignant neoplasms affecting the bone marrow or lymphatic system. Immunosuppressive therapy (including high-dose corticosteroids). Primary & acquired immunodeficiency states. Family history of congenital or hereditary immunodeficiency. Active untreated TB. Any active febrile illness w/ fever >38.5°C. Pregnancy (3 mth following vaccination).
Hypersensitivity to eggs. History of convulsions, cerebral injury or any other condition in which stress due to fever should be avoided. HIV w/ or w/o evidence of immunosuppression. Avoid close association w/ high-risk individuals (immunocompromised individuals, pregnant women & their newborn w/o documented +ve history of chickenpox or lab evidence of prior varicella infection) susceptible to varicella for up to 6 wk following vaccination. Individuals w/ thrombocytopenia. Temporary depression of tuberculin skin sensitivity. Theoretical risk for transmission of Creutzfeldt-Jakob (CJD) disease. At least 1 mth should elapse between a dose of Attenuvax or MMR II & ProQuad. Pregnant women or women who become pregnant w/in 3 mth of vaccination & lactation. Not recommended for infant <12 mth.
Fever ≥38.9°C, erythema or pain/tenderness/soreness at the inj site. Upper resp infection; irritability; diarrhea, vomiting; measles-like rash; varicella-like rash; ecchymosis or swelling at the inj site, inj site rash.
Drug Interactions
May interfere w/ the expected immune response w/ Ig. Defer vaccination at least 3 mth following blood/plasma transfusion or Ig administration & 5 mth for VZIg. At least 1 mth should elapse between a dose of Attenuvax or MMR II & Proquad. Risk of Reye syndrome w/ salicylates (6 wk after vaccination).
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