Pegstim

Pegstim

pegfilgrastim

Manufacturer:

Zydus Healthcare

Distributor:

Zydus Healthcare
Concise Prescribing Info
Contents
Pegfilgrastim
Indications/Uses
Reduction in duration of neutropenia & incidence of febrile neutropenia in patients treated w/ cytotoxic chemotherapy for malignancy. Decrease the risk of febrile neutropenia in patients w/ non-myeloid malignancies receiving myelosuppressive antineoplastic cytotoxic chemotherapy that is associated w/ clinically important risk of severe neutropenia w/ fever.
Dosage/Direction for Use
SC Adult Chemotherapy induced neutropenia 6 mg single dose once per chemotherapy cycle.
Contraindications
Hypersensitivity to pegfilgrastim, filgrastim or proteins derived from E. coli.
Special Precautions
Splenic rupture; adult resp distress syndrome; sickle cell disease; permanently discontinue in patients w/ serious allergic reactions. Do not administer during 14 days before or 24 hr after cytotoxic chemotherapy. Potential effect on malignant cells; bone pain. Pregnancy & lactation. Infant, childn & adolescent <45 kg.
Adverse Reactions
Mild-to-moderate medullary bone pain. Nausea, fatigue, alopecia, diarrhea, vomiting, constipation, fever, anorexia, skeletal pain, headache, taste perversion, dyspepsia, myalgia, insomnia, abdominal pain, arthralgia, generalized weakness, peripheral edema, dizziness, granulocytopenia, stomatitis, mucositis & neutropenic fever.
Drug Interactions
Potentiation of neutrophils release w/ lithium.
MIMS Class
Haematopoietic Agents / Supportive Care Therapy
ATC Classification
L03AA13 - pegfilgrastim ; Belongs to the class of colony stimulating factors. Used as immunostimulants.
Presentation/Packing
Form
Pegstim soln for inj 6 mg/0.6 mL
Packing/Price
0.6 mL x 1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in