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The usual recommended adult dose is 10 mg for 70 kg individual administered SC, IM or IV; this dose may be repeated every 3 to 6 hours as necessary. Dosage should be adjusted according to the severity of the pain, physical status of the patients, and other medications which the patients may be receiving, see Interactions (Other CNS depressants). In non-tolerant individuals, the recommended single maximum dose is 20 mg, with a maximum total daily dose of 160 mg.
The use of Nalbuphine as a supplement to balanced anesthesia requires larger doses than those recommended for analgesic. Induction doses of Nalbuphine range from 0.3-3 mg/kg IV to be administered over 10 to 15 minute period with maintenance doses of 0.25-0.50 mg/ kg in single IV administration as required.
Or as prescribed by a physician.
